The SonoSite L25 series needle guidance system uses a two-part system consisting of a reusable needle guide bracket and disposable snap-on needle guide. The sterile disposable needle guide snaps on the bracket, providing a fixed path for visualizing ultrasound-guided vascular access and nerve block procedures. The guide features a mechanism for quick-release detachment of the needle from the guide while maintaining secure needle placement once the targeted depth has been reached.